Predictive values of immature granulocyte and other inflammatory parameters on disease severity of COVID?19 patients

INTRODUCTION: This study was designed to compare the immature granulocyte (IG) count, IG-to-lymphocyte ratio (IGLR), complete blood count (CBC) values, and inflammatory parameters of neutrophil-to-lymphocyte (NLR), platelet-to-lymphocyte (PLR), C-reactive protein (CRP), ferritin level, CRP-to-albumin (CAR) measured at hospital admission in patients with coronavirus disease 2019 (COVID-19) non-COVID-19 these between subgroups according severity. In addition, were evaluated for predictive value related severity COVID-19. METHODS: The data adult admitted a suspected COVID-19 infection confirmed real-time polymerase chain reaction testing nasal pharyngeal swab specimens included this retrospective study. Outpatient COVID-19-positive enrolled mild group, hospitalized classified moderate intensive care unit categorized severe group. RESULTS: A total 1213 1034 COVID-19-negative IGLR, NLR, PLR, CRP, CAR, levels significantly higher, leukocyte, IG, neutrophil, lymphocyte, monocyte, basophil, eosinophil lower group than (p<0.05 all). had higher median PLR mild, moderate, groups Receiver operating characteristic analysis revealed an area under curve 0.868, 0.860, 0.834, 0.848, 0.845, 0.841, 0.827, respectively, which differentiated from patients. DISCUSSION AND CONCLUSION: results suggest that IGLR may be useful distinguish time admission. Further exploration is warranted fully determine potential monitoring.